Saint Charles, Missouri to Sioux Falls: Road Trip Guide & Distance

462.1 miles 743.6 km · straight line
554.4 miles estimated 892.3 km · driving distance
11h 9min estimated drive time
$53 - $66 estimated fuel cost
~1h 26min flight time
317° NW bearing direction

How far is Saint Charles, Missouri from Sioux Falls?

The distance from Saint Charles, Missouri to Sioux Falls is 462.1 miles (743.6 km) as the crow flies. Sioux Falls is located NW of Saint Charles, Missouri. By car, the driving distance is approximately 554.4 miles, taking about 11h 9min. A direct flight would take roughly 1h 26min. Both are located in United States — Saint Charles, Missouri in Missouri and Sioux Falls in South Dakota.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Saint Charles, Missouri and Sioux Falls. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.

How to Get from Saint Charles, Missouri to Sioux Falls

Method Time Est. Cost Best For
Drive 11h 9min $53 - $66 Flexible stops
Fly ~1h 26min $80–200* Speed
Bus ~13h 23min $44–$83* Budget
Train ~10h 36min $67–$194* Comfort

Suggested Stops Between Saint Charles, Missouri & Sioux Falls

Quick Facts

Saint Charles, Missouri
38.78°N, 90.48°W
America/Chicago
147m elevation
Sioux Falls
43.54°N, 96.73°W
America/Chicago
448m elevation
Explore more routes from Sioux Falls

Did You Know?

  • At walking speed (3 mph), it would take about 154 hours of non-stop walking
  • By bicycle at 12 mph, the journey would take roughly 39 hours
  • You could travel this distance about 53.9 times to circle the Earth's equator
Data Sources & Estimate Notes GeoNames · OpenStreetMap · Driving distance estimated using road factor coefficients