Knoxville to Saint Joseph: Road Trip Guide & Distance

650.9 miles 1047.5 km · straight line
781.1 miles estimated 1257 km · driving distance
15h 43min estimated drive time
$75 - $93 estimated fuel cost
~1h 49min flight time
297° WNW bearing direction

How far is Knoxville from Saint Joseph?

The distance from Knoxville to Saint Joseph is 650.9 miles (1047.5 km) as the crow flies. Saint Joseph is located WNW of Knoxville. By car, the driving distance is approximately 781.1 miles, taking about 15h 43min. A direct flight would take roughly 1h 49min. Both are located in United States — Knoxville in Tennessee and Saint Joseph in Missouri.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Knoxville and Saint Joseph. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.

How to Get from Knoxville to Saint Joseph

Method Time Est. Cost Best For
Drive 15h 43min $75 - $93 Flexible stops
Fly ~1h 49min $80–200* Speed
Bus ~18h 52min $62–$117* Budget
Train ~20h 26min $94–$273* Comfort

Suggested Stops Between Knoxville & Saint Joseph

Quick Facts

Knoxville
35.96°N, 83.92°W
America/New_York
276m elevation
Saint Joseph
39.77°N, 94.85°W
America/Chicago
270m elevation
Explore more routes from Saint Joseph

Did You Know?

  • At walking speed (3 mph), it would take about 217 hours of non-stop walking
  • By bicycle at 12 mph, the journey would take roughly 54 hours
  • You could travel this distance about 38.3 times to circle the Earth's equator
Data Sources & Estimate Notes GeoNames · OpenStreetMap · Driving distance estimated using road factor coefficients