Knoxville to O'Fallon, Missouri: Road Trip Guide & Distance
How far is Knoxville from O'Fallon, Missouri?
The distance from Knoxville to O'Fallon, Missouri is 420.9 miles (677.4 km) as the crow flies. O'Fallon, Missouri is located WNW of Knoxville. By car, the driving distance is approximately 505.1 miles, taking about 10h 10min. A direct flight would take roughly 1h 21min. Both are located in United States — Knoxville in Tennessee and O'Fallon, Missouri in Missouri.
This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.
Coordinates come from public place data for Knoxville and O'Fallon, Missouri. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.
How to Get from Knoxville to O'Fallon, Missouri
Suggested Stops Between Knoxville & O'Fallon, Missouri
- 1244 mi
- 2157 mi
- 3216 mi
- 4376 mi
- 5240 mi
Quick Facts
Did You Know?
- At walking speed (3 mph), it would take about 140 hours of non-stop walking
- By bicycle at 12 mph, the journey would take roughly 35 hours
- You could travel this distance about 59.2 times to circle the Earth's equator