Columbia, Missouri to Knoxville: Road Trip Guide & Distance
How far is Columbia, Missouri from Knoxville?
The distance from Columbia, Missouri to Knoxville is 505.4 miles (813.3 km) as the crow flies. Knoxville is located ESE of Columbia, Missouri. By car, the driving distance is approximately 606.5 miles, taking about 12h 12min. A direct flight would take roughly 1h 31min. Both are located in United States — Columbia, Missouri in Missouri and Knoxville in Tennessee.
This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.
Coordinates come from public place data for Columbia, Missouri and Knoxville. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.
How to Get from Columbia, Missouri to Knoxville
Suggested Stops Between Columbia, Missouri & Knoxville
- 1117 mi
- 288 mi
- 3100 mi
- 4348 mi
- 593 mi
Quick Facts
Did You Know?
- At walking speed (3 mph), it would take about 168 hours of non-stop walking
- By bicycle at 12 mph, the journey would take roughly 42 hours
- You could travel this distance about 49.3 times to circle the Earth's equator