Alton, Illinois to Knoxville: Road Trip Guide & Distance

How far is Alton, Illinois from Knoxville?

The distance from Alton, Illinois to Knoxville is 398.7 miles (641.7 km) as the crow flies. Knoxville is located ESE of Alton, Illinois. By car, the driving distance is approximately 478.5 miles, taking about 9h 38min. A direct flight would take roughly 1h 18min. Both are located in United States — Alton, Illinois in Illinois and Knoxville in Tennessee.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Alton, Illinois and Knoxville. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.