Knoxville to Madisonville: Road Trip Guide & Distance

How far is Knoxville from Madisonville?

The distance from Knoxville to Madisonville is 219.7 miles (353.6 km) as the crow flies. Madisonville is located WNW of Knoxville. By car, the driving distance is approximately 274.6 miles, taking about 5h 32min. A direct flight would take roughly 57min. Both are located in United States — Knoxville in Tennessee and Madisonville in Kentucky.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Knoxville and Madisonville. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.