Knoxville to Wilson: Road Trip Guide & Distance

How far is Knoxville from Wilson?

The distance from Knoxville to Wilson is 336.7 miles (541.9 km) as the crow flies. Wilson is located E of Knoxville. By car, the driving distance is approximately 404.1 miles, taking about 8h 8min. A direct flight would take roughly 1h 11min. Both are located in United States — Knoxville in Tennessee and Wilson in North Carolina.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Knoxville and Wilson. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.