Columbia, Missouri to Winston-Salem: Road Trip Guide & Distance

How far is Columbia, Missouri from Winston-Salem?

The distance from Columbia, Missouri to Winston-Salem is 690.5 miles (1111.3 km) as the crow flies. Winston-Salem is located ESE of Columbia, Missouri. By car, the driving distance is approximately 828.7 miles, taking about 16h 40min. A direct flight would take roughly 1h 53min. Both are located in United States — Columbia, Missouri in Missouri and Winston-Salem in North Carolina.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility. For a trip of this distance, flying is significantly faster. However, driving offers the flexibility to explore stops along the way.

Coordinates come from public place data for Columbia, Missouri and Winston-Salem. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.