St. Louis to Winston-Salem: Road Trip Guide & Distance
How far is St. Louis from Winston-Salem?
The distance from St. Louis to Winston-Salem is 573.5 miles (923 km) as the crow flies. Winston-Salem is located ESE of St. Louis. By car, the driving distance is approximately 688.2 miles, taking about 13h 51min. A direct flight would take roughly 1h 39min. Both are located in United States — St. Louis in Missouri and Winston-Salem in North Carolina.
This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.
Coordinates come from public place data for St. Louis and Winston-Salem. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.
How to Get from St. Louis to Winston-Salem
Suggested Stops Between St. Louis & Winston-Salem
- 1150 mi
- 2459 mi
- 3178 mi
- 4442 mi
- 5244 mi
Quick Facts
Did You Know?
- At walking speed (3 mph), it would take about 191 hours of non-stop walking
- By bicycle at 12 mph, the journey would take roughly 48 hours
- You could travel this distance about 43.4 times to circle the Earth's equator