Cicero to Knoxville: Road Trip Guide & Distance

How far is Cicero from Knoxville?

The distance from Cicero to Knoxville is 648.3 miles (1043.4 km) as the crow flies. Knoxville is located SW of Cicero. By car, the driving distance is approximately 778 miles, taking about 15h 39min. A direct flight would take roughly 1h 48min. Both are located in United States — Cicero in New York and Knoxville in Tennessee.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Cicero and Knoxville. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.