Cape Girardeau to Reading, Pennsylvania: Road Trip Guide & Distance

How far is Cape Girardeau from Reading, Pennsylvania?

The distance from Cape Girardeau to Reading, Pennsylvania is 760.1 miles (1223.3 km) as the crow flies. Reading, Pennsylvania is located ENE of Cape Girardeau. By car, the driving distance is approximately 912.2 miles, taking about 18h 21min. A direct flight would take roughly 2h 2min. Both are located in United States — Cape Girardeau in Missouri and Reading, Pennsylvania in Pennsylvania.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility. For a trip of this distance, flying is significantly faster. However, driving offers the flexibility to explore stops along the way.

Coordinates come from public place data for Cape Girardeau and Reading, Pennsylvania. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.