Cape Girardeau to Louisville: Road Trip Guide & Distance

215.5 miles 346.8 km · straight line
274.4 miles actual route 441.6 km · driving distance
5h 9min estimated drive time
$26 - $33 estimated fuel cost
~56min flight time
71° ENE bearing direction

How far is Cape Girardeau from Louisville?

The distance from Cape Girardeau to Louisville is 215.5 miles (346.8 km) as the crow flies. Louisville is located ENE of Cape Girardeau. By car, the driving distance is approximately 274.4 miles, taking about 5h 9min. A direct flight would take roughly 56min. Both are located in United States — Cape Girardeau in Missouri and Louisville in Kentucky.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Cape Girardeau and Louisville. The driving distance uses an OSRM road-route result when route data is available. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.

How to Get from Cape Girardeau to Louisville

Method Time Est. Cost Best For
Drive 5h 9min $26 - $33 Flexible stops
Fly ~56min $80–200* Speed
Bus ~6h 11min $22–$41* Budget
Train ~4h 54min $33–$96* Comfort

Suggested Stops Between Cape Girardeau & Louisville

Quick Facts

Cape Girardeau
37.31°N, 89.52°W
America/Chicago
108m elevation
Louisville
38.25°N, 85.76°W
America/New_York
142m elevation
Explore more routes from Louisville

Did You Know?

  • At walking speed (3 mph), it would take about 72 hours of non-stop walking
  • By bicycle at 12 mph, the journey would take roughly 18 hours
  • You could travel this distance about 115.6 times to circle the Earth's equator
Data Sources & Estimate Notes GeoNames · OpenStreetMap · OSRM