Reading, Pennsylvania to St. Louis: Road Trip Guide & Distance

How far is Reading, Pennsylvania from St. Louis?

The distance from Reading, Pennsylvania to St. Louis is 769.4 miles (1238.2 km) as the crow flies. St. Louis is located W of Reading, Pennsylvania. By car, the driving distance is approximately 923.2 miles, taking about 18h 34min. A direct flight would take roughly 2h 3min. Both are located in United States — Reading, Pennsylvania in Pennsylvania and St. Louis in Missouri.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare. For a trip of this distance, flying is significantly faster. However, driving offers the flexibility to explore stops along the way.

Coordinates come from public place data for Reading, Pennsylvania and St. Louis. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.