Dayton to St. Louis: Road Trip Guide & Distance

How far is Dayton from St. Louis?

The distance from Dayton to St. Louis is 331 miles (532.7 km) as the crow flies. St. Louis is located WSW of Dayton. By car, the driving distance is approximately 397.2 miles, taking about 7h 59min. A direct flight would take roughly 1h 10min. Both are located in United States — Dayton in Ohio and St. Louis in Missouri.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Dayton and St. Louis. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.