Port Saint Lucie to Roanoke: Road Trip Guide & Distance

How far is Port Saint Lucie from Roanoke?

The distance from Port Saint Lucie to Roanoke is 689.8 miles (1110.1 km) as the crow flies. Roanoke is located N of Port Saint Lucie. By car, the driving distance is approximately 827.7 miles, taking about 16h 39min. A direct flight would take roughly 1h 53min. Both are located in United States — Port Saint Lucie in Florida and Roanoke in Virginia.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Heading North for this distance usually means noticeable weather changes. Make sure to check the forecast for your destination before hitting the road. For a trip of this distance, flying is significantly faster. However, driving offers the flexibility to explore stops along the way.

Coordinates come from public place data for Port Saint Lucie and Roanoke. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.