O'Fallon, Missouri to San Angelo: Road Trip Guide & Distance

How far is O'Fallon, Missouri from San Angelo?

The distance from O'Fallon, Missouri to San Angelo is 747.8 miles (1203.4 km) as the crow flies. San Angelo is located SW of O'Fallon, Missouri. By car, the driving distance is approximately 897.3 miles, taking about 18h 3min. A direct flight would take roughly 2h 0min. Both are located in United States — O'Fallon, Missouri in Missouri and San Angelo in Texas.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare. For a trip of this distance, flying is significantly faster. However, driving offers the flexibility to explore stops along the way.

Coordinates come from public place data for O'Fallon, Missouri and San Angelo. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.