Mattoon to Tupelo: Road Trip Guide & Distance

How far is Mattoon from Tupelo?

The distance from Mattoon to Tupelo is 361.5 miles (581.7 km) as the crow flies. Tupelo is located S of Mattoon. By car, the driving distance is approximately 433.7 miles, taking about 8h 44min. A direct flight would take roughly 1h 14min. Both are located in United States — Mattoon in Illinois and Tupelo in Mississippi.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. As you head South, expect warmer temperatures. Make sure your car's AC is working well before embarking on this journey.

Coordinates come from public place data for Mattoon and Tupelo. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.