Mount Vernon, Illinois to Tupelo: Road Trip Guide & Distance

How far is Mount Vernon, Illinois from Tupelo?

The distance from Mount Vernon, Illinois to Tupelo is 280.7 miles (451.7 km) as the crow flies. Tupelo is located S of Mount Vernon, Illinois. By car, the driving distance is approximately 350.8 miles, taking about 7h 3min. A direct flight would take roughly 1h 4min. Both are located in United States — Mount Vernon, Illinois in Illinois and Tupelo in Mississippi.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee.

Coordinates come from public place data for Mount Vernon, Illinois and Tupelo. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.