Knoxville to Orlando: Road Trip Guide & Distance

How far is Knoxville from Orlando?

The distance from Knoxville to Orlando is 533.8 miles (859.1 km) as the crow flies. Orlando is located SSE of Knoxville. By car, the driving distance is approximately 640.6 miles, taking about 12h 53min. A direct flight would take roughly 1h 34min. Both are located in United States — Knoxville in Tennessee and Orlando in Florida.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Knoxville and Orlando. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.