Knoxville to St. Johns: Road Trip Guide & Distance

How far is Knoxville from St. Johns?

The distance from Knoxville to St. Johns is 428.8 miles (690.1 km) as the crow flies. St. Johns is located SSE of Knoxville. By car, the driving distance is approximately 514.6 miles, taking about 10h 21min. A direct flight would take roughly 1h 22min. Both are located in United States — Knoxville in Tennessee and St. Johns in Florida.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Knoxville and St. Johns. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.