Knoxville to Mesa: Road Trip Guide & Distance

How far is Knoxville from Mesa?

The distance from Knoxville to Mesa is 1590 miles (2558.8 km) as the crow flies. Mesa is located W of Knoxville. By car, the driving distance is approximately 1804.2 miles, taking about 31h 57min. A direct flight would take roughly 3h 42min. Both are located in United States — Knoxville in Tennessee and Mesa in Arizona.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare. For a trip of this distance, flying is significantly faster. However, driving offers the flexibility to explore stops along the way.

Coordinates come from public place data for Knoxville and Mesa. The driving distance uses an OSRM road-route result when route data is available. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.