Knoxville to Lake Charles: Road Trip Guide & Distance

How far is Knoxville from Lake Charles?

The distance from Knoxville to Lake Charles is 667.7 miles (1074.5 km) as the crow flies. Lake Charles is located SW of Knoxville. By car, the driving distance is approximately 801.2 miles, taking about 16h 7min. A direct flight would take roughly 1h 51min. Both are located in United States — Knoxville in Tennessee and Lake Charles in Louisiana.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare. For a trip of this distance, flying is significantly faster. However, driving offers the flexibility to explore stops along the way.

Coordinates come from public place data for Knoxville and Lake Charles. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.