Alexandria to Knoxville: Road Trip Guide & Distance

How far is Alexandria from Knoxville?

The distance from Alexandria to Knoxville is 585.8 miles (942.8 km) as the crow flies. Knoxville is located NE of Alexandria. By car, the driving distance is approximately 703 miles, taking about 14h 9min. A direct flight would take roughly 1h 41min. Both are located in United States — Alexandria in Louisiana and Knoxville in Tennessee.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Alexandria and Knoxville. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.