Kirksville to Louisville: Road Trip Guide & Distance

389 miles 626.1 km · straight line
468.1 miles actual route 753.4 km · driving distance
8h 57min estimated drive time
$45 - $55 estimated fuel cost
~1h 17min flight time
108° ESE bearing direction

How far is Kirksville from Louisville?

The distance from Kirksville to Louisville is 389 miles (626.1 km) as the crow flies. Louisville is located ESE of Kirksville. By car, the driving distance is approximately 468.1 miles, taking about 8h 57min. A direct flight would take roughly 1h 17min. Both are located in United States — Kirksville in Missouri and Louisville in Kentucky.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Kirksville and Louisville. The driving distance uses an OSRM road-route result when route data is available. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.

How to Get from Kirksville to Louisville

Method Time Est. Cost Best For
Drive 8h 57min $45 - $55 Flexible stops
Fly ~1h 17min $80–200* Speed
Bus ~10h 44min $37–$70* Budget
Train ~8h 30min $56–$164* Comfort

Suggested Stops Between Kirksville & Louisville

Quick Facts

Kirksville
40.19°N, 92.58°W
America/Chicago
299m elevation
Louisville
38.25°N, 85.76°W
America/New_York
142m elevation
Explore more routes from Louisville

Did You Know?

  • At walking speed (3 mph), it would take about 130 hours of non-stop walking
  • By bicycle at 12 mph, the journey would take roughly 32 hours
  • You could travel this distance about 64 times to circle the Earth's equator
Data Sources & Estimate Notes GeoNames · OpenStreetMap · OSRM