Kirksville to Vincennes: Road Trip Guide & Distance

How far is Kirksville from Vincennes?

The distance from Kirksville to Vincennes is 289.3 miles (465.6 km) as the crow flies. Vincennes is located ESE of Kirksville. By car, the driving distance is approximately 361.6 miles, taking about 7h 17min. A direct flight would take roughly 1h 5min. Both are located in United States — Kirksville in Missouri and Vincennes in Indiana.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Kirksville and Vincennes. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.