Jamestown, New York to Knoxville: Road Trip Guide & Distance

How far is Jamestown, New York from Knoxville?

The distance from Jamestown, New York to Knoxville is 492.7 miles (793 km) as the crow flies. Knoxville is located SSW of Jamestown, New York. By car, the driving distance is approximately 591.3 miles, taking about 11h 54min. A direct flight would take roughly 1h 29min. Both are located in United States — Jamestown, New York in New York and Knoxville in Tennessee.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Jamestown, New York and Knoxville. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.