Indianapolis to Knoxville: Road Trip Guide & Distance

How far is Indianapolis from Knoxville?

The distance from Indianapolis to Knoxville is 290 miles (466.7 km) as the crow flies. Knoxville is located SSE of Indianapolis. By car, the driving distance is approximately 356.7 miles, taking about 6h 36min. A direct flight would take roughly 1h 5min. Both are located in United States — Indianapolis in Indiana and Knoxville in Tennessee.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Indianapolis and Knoxville. The driving distance uses an OSRM road-route result when route data is available. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.