Great Smoky Mountains to Lafayette, Indiana: Road Trip Guide & Distance

How far is Great Smoky Mountains from Lafayette, Indiana?

The distance from Great Smoky Mountains to Lafayette, Indiana is 379.7 miles (611 km) as the crow flies. Lafayette, Indiana is located NNW of Great Smoky Mountains. By car, the driving distance is approximately 455.6 miles, taking about 9h 10min. A direct flight would take roughly 1h 16min. Both are located in United States — Great Smoky Mountains in Tennessee and Lafayette, Indiana in Indiana.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Great Smoky Mountains and Lafayette, Indiana. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.