Great Smoky Mountains to Louisville: Road Trip Guide & Distance

How far is Great Smoky Mountains from Louisville?

The distance from Great Smoky Mountains to Louisville is 221.3 miles (356.2 km) as the crow flies. Louisville is located NW of Great Smoky Mountains. By car, the driving distance is approximately 291.7 miles, taking about 5h 46min. A direct flight would take roughly 57min. Both are located in United States — Great Smoky Mountains in Tennessee and Louisville in Kentucky.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Great Smoky Mountains and Louisville. The driving distance uses an OSRM road-route result when route data is available. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.