Gainesville, Florida to Jackson, Mississippi: Road Trip Guide & Distance

How far is Gainesville, Florida from Jackson, Mississippi?

The distance from Gainesville, Florida to Jackson, Mississippi is 500.1 miles (804.8 km) as the crow flies. Jackson, Mississippi is located WNW of Gainesville, Florida. By car, the driving distance is approximately 600.1 miles, taking about 12h 4min. A direct flight would take roughly 1h 30min. Both are located in United States — Gainesville, Florida in Florida and Jackson, Mississippi in Mississippi.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Gainesville, Florida and Jackson, Mississippi. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.