Enterprise to Gainesville, Florida: Road Trip Guide & Distance

How far is Enterprise from Gainesville, Florida?

The distance from Enterprise to Gainesville, Florida is 239.5 miles (385.5 km) as the crow flies. Gainesville, Florida is located ESE of Enterprise. By car, the driving distance is approximately 299.4 miles, taking about 6h 1min. A direct flight would take roughly 59min. Both are located in United States — Enterprise in Alabama and Gainesville, Florida in Florida.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Enterprise and Gainesville, Florida. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.