Florence, Alabama to O'Fallon, Illinois: Road Trip Guide & Distance

How far is Florence, Alabama from O'Fallon, Illinois?

The distance from Florence, Alabama to O'Fallon, Illinois is 289.7 miles (466.3 km) as the crow flies. O'Fallon, Illinois is located NNW of Florence, Alabama. By car, the driving distance is approximately 362.2 miles, taking about 7h 17min. A direct flight would take roughly 1h 5min. Both are located in United States — Florence, Alabama in Alabama and O'Fallon, Illinois in Illinois.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Florence, Alabama and O'Fallon, Illinois. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.