Cape Girardeau to Florence, Alabama: Road Trip Guide & Distance

201.4 miles 324.1 km · straight line
251.7 miles estimated 405.1 km · driving distance
5h 4min estimated drive time
$24 - $30 estimated fuel cost
~54min flight time
149° SSE bearing direction

How far is Cape Girardeau from Florence, Alabama?

The distance from Cape Girardeau to Florence, Alabama is 201.4 miles (324.1 km) as the crow flies. Florence, Alabama is located SSE of Cape Girardeau. By car, the driving distance is approximately 251.7 miles, taking about 5h 4min. A direct flight would take roughly 54min. Both are located in United States — Cape Girardeau in Missouri and Florence, Alabama in Alabama.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Cape Girardeau and Florence, Alabama. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.

How to Get from Cape Girardeau to Florence, Alabama

Method Time Est. Cost Best For
Drive 5h 4min $24 - $30 Flexible stops
Fly ~54min $80–200* Speed
Bus ~6h 5min $20–$38* Budget
Train ~4h 49min $30–$88* Comfort

Suggested Stops Between Cape Girardeau & Florence, Alabama

Quick Facts

Cape Girardeau
37.31°N, 89.52°W
America/Chicago
108m elevation
Florence, Alabama
34.80°N, 87.68°W
America/Chicago
167m elevation
Explore more routes from Florence, Alabama

Did You Know?

  • At walking speed (3 mph), it would take about 67 hours of non-stop walking
  • By bicycle at 12 mph, the journey would take roughly 17 hours
  • You could travel this distance about 123.7 times to circle the Earth's equator
Data Sources & Estimate Notes GeoNames · OpenStreetMap · Driving distance estimated using road factor coefficients