Durham, North Carolina to St. Louis: Road Trip Guide & Distance
How far is Durham, North Carolina from St. Louis?
The distance from Durham, North Carolina to St. Louis is 646.6 miles (1040.6 km) as the crow flies. St. Louis is located WNW of Durham, North Carolina. By car, the driving distance is approximately 775.9 miles, taking about 15h 37min. A direct flight would take roughly 1h 48min. Both are located in United States — Durham, North Carolina in North Carolina and St. Louis in Missouri.
This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.
Coordinates come from public place data for Durham, North Carolina and St. Louis. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.
How to Get from Durham, North Carolina to St. Louis
Suggested Stops Between Durham, North Carolina & St. Louis
- 176 mi
- 2497 mi
- 3470 mi
- 4208 mi
- 5322 mi
Quick Facts
Did You Know?
- At walking speed (3 mph), it would take about 216 hours of non-stop walking
- By bicycle at 12 mph, the journey would take roughly 54 hours
- You could travel this distance about 38.5 times to circle the Earth's equator