Durham, North Carolina to Fort Myers: Road Trip Guide & Distance

How far is Durham, North Carolina from Fort Myers?

The distance from Durham, North Carolina to Fort Myers is 669.6 miles (1077.6 km) as the crow flies. Fort Myers is located SSW of Durham, North Carolina. By car, the driving distance is approximately 803.5 miles, taking about 16h 10min. A direct flight would take roughly 1h 51min. Both are located in United States — Durham, North Carolina in North Carolina and Fort Myers in Florida.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare. For a trip of this distance, flying is significantly faster. However, driving offers the flexibility to explore stops along the way.

Coordinates come from public place data for Durham, North Carolina and Fort Myers. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.