Des Moines to Republic: Road Trip Guide & Distance

How far is Des Moines from Republic?

The distance from Des Moines to Republic is 308.7 miles (496.8 km) as the crow flies. Republic is located S of Des Moines. By car, the driving distance is approximately 385.9 miles, taking about 7h 46min. A direct flight would take roughly 1h 7min. Both are located in United States — Des Moines in Iowa and Republic in Missouri.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time.

Coordinates come from public place data for Des Moines and Republic. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.