Deltona to Knoxville: Road Trip Guide & Distance

How far is Deltona from Knoxville?

The distance from Deltona to Knoxville is 511.8 miles (823.6 km) as the crow flies. Knoxville is located NNW of Deltona. By car, the driving distance is approximately 614.1 miles, taking about 12h 21min. A direct flight would take roughly 1h 32min. Both are located in United States — Deltona in Florida and Knoxville in Tennessee.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Deltona and Knoxville. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.