Danville, Virginia to Knoxville: Road Trip Guide & Distance

How far is Danville, Virginia from Knoxville?

The distance from Danville, Virginia to Knoxville is 255.8 miles (411.6 km) as the crow flies. Knoxville is located W of Danville, Virginia. By car, the driving distance is approximately 319.7 miles, taking about 6h 26min. A direct flight would take roughly 1h 1min. Both are located in United States — Danville, Virginia in Virginia and Knoxville in Tennessee.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Danville, Virginia and Knoxville. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.