Columbia, Tennessee to O'Fallon, Missouri: Road Trip Guide & Distance

How far is Columbia, Tennessee from O'Fallon, Missouri?

The distance from Columbia, Tennessee to O'Fallon, Missouri is 298.9 miles (481.1 km) as the crow flies. O'Fallon, Missouri is located NW of Columbia, Tennessee. By car, the driving distance is approximately 373.7 miles, taking about 7h 31min. A direct flight would take roughly 1h 6min. Both are located in United States — Columbia, Tennessee in Tennessee and O'Fallon, Missouri in Missouri.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Columbia, Tennessee and O'Fallon, Missouri. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.