Columbia, South Carolina to St. Louis: Road Trip Guide & Distance

601.6 miles 968.2 km · straight line
721.9 miles estimated 1161.8 km · driving distance
14h 31min estimated drive time
$69 - $86 estimated fuel cost
~1h 43min flight time
305° NW bearing direction

How far is Columbia, South Carolina from St. Louis?

The distance from Columbia, South Carolina to St. Louis is 601.6 miles (968.2 km) as the crow flies. St. Louis is located NW of Columbia, South Carolina. By car, the driving distance is approximately 721.9 miles, taking about 14h 31min. A direct flight would take roughly 1h 43min. Both are located in United States — Columbia, South Carolina in South Carolina and St. Louis in Missouri.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Columbia, South Carolina and St. Louis. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.

How to Get from Columbia, South Carolina to St. Louis

Method Time Est. Cost Best For
Drive 14h 31min $69 - $86 Flexible stops
Fly ~1h 43min $80–200* Speed
Bus ~17h 25min $58–$108* Budget
Train ~18h 52min $87–$253* Comfort

Suggested Stops Between Columbia, South Carolina & St. Louis

Quick Facts

Columbia, South Carolina
34.00°N, 81.03°W
America/New_York
89m elevation
St. Louis
38.63°N, 90.20°W
America/Chicago
142m elevation
Explore more routes from St. Louis

Did You Know?

  • At walking speed (3 mph), it would take about 201 hours of non-stop walking
  • By bicycle at 12 mph, the journey would take roughly 50 hours
  • You could travel this distance about 41.4 times to circle the Earth's equator
Data Sources & Estimate Notes GeoNames · OpenStreetMap · Driving distance estimated using road factor coefficients