Cocoa to Florence, South Carolina: Road Trip Guide & Distance

How far is Cocoa from Florence, South Carolina?

The distance from Cocoa to Florence, South Carolina is 405.5 miles (652.6 km) as the crow flies. Florence, South Carolina is located N of Cocoa. By car, the driving distance is approximately 486.6 miles, taking about 9h 47min. A direct flight would take roughly 1h 19min. Both are located in United States — Cocoa in Florida and Florence, South Carolina in South Carolina.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading North for this distance usually means noticeable weather changes. Make sure to check the forecast for your destination before hitting the road.

Coordinates come from public place data for Cocoa and Florence, South Carolina. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.