Carbondale to Knoxville: Road Trip Guide & Distance

How far is Carbondale from Knoxville?

The distance from Carbondale to Knoxville is 317.2 miles (510.5 km) as the crow flies. Knoxville is located ESE of Carbondale. By car, the driving distance is approximately 380.7 miles, taking about 7h 39min. A direct flight would take roughly 1h 8min. Both are located in United States — Carbondale in Illinois and Knoxville in Tennessee.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Carbondale and Knoxville. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.