Hopkinsville to Knoxville: Road Trip Guide & Distance

How far is Hopkinsville from Knoxville?

The distance from Hopkinsville to Knoxville is 208.2 miles (335 km) as the crow flies. Knoxville is located ESE of Hopkinsville. By car, the driving distance is approximately 260.2 miles, taking about 5h 14min. A direct flight would take roughly 55min. Both are located in United States — Hopkinsville in Kentucky and Knoxville in Tennessee.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Hopkinsville and Knoxville. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.