Cape Girardeau to Oklahoma City: Road Trip Guide & Distance

How far is Cape Girardeau from Oklahoma City?

The distance from Cape Girardeau to Oklahoma City is 462.5 miles (744.3 km) as the crow flies. Oklahoma City is located WSW of Cape Girardeau. By car, the driving distance is approximately 551 miles, taking about 10h 14min. A direct flight would take roughly 1h 26min. Both are located in United States — Cape Girardeau in Missouri and Oklahoma City in Oklahoma.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Cape Girardeau and Oklahoma City. The driving distance uses an OSRM road-route result when route data is available. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.