Buffalo, New York to Winston-Salem: Road Trip Guide & Distance

How far is Buffalo, New York from Winston-Salem?

The distance from Buffalo, New York to Winston-Salem is 474.5 miles (763.6 km) as the crow flies. Winston-Salem is located S of Buffalo, New York. By car, the driving distance is approximately 569.4 miles, taking about 11h 27min. A direct flight would take roughly 1h 27min. Both are located in United States — Buffalo, New York in New York and Winston-Salem in North Carolina.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. As you head South, expect warmer temperatures. Make sure your car's AC is working well before embarking on this journey.

Coordinates come from public place data for Buffalo, New York and Winston-Salem. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.