Appleton to Sioux Falls: Road Trip Guide & Distance

How far is Appleton from Sioux Falls?

The distance from Appleton to Sioux Falls is 416.6 miles (670.5 km) as the crow flies. Sioux Falls is located W of Appleton. By car, the driving distance is approximately 500 miles, taking about 10h 3min. A direct flight would take roughly 1h 20min. Both are located in United States — Appleton in Wisconsin and Sioux Falls in South Dakota.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Appleton and Sioux Falls. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.