Wilmington, Delaware to Winston-Salem: Road Trip Guide & Distance

How far is Wilmington, Delaware from Winston-Salem?

The distance from Wilmington, Delaware to Winston-Salem is 359.1 miles (577.9 km) as the crow flies. Winston-Salem is located SW of Wilmington, Delaware. By car, the driving distance is approximately 430.9 miles, taking about 8h 40min. A direct flight would take roughly 1h 13min. Both are located in United States — Wilmington, Delaware in Delaware and Winston-Salem in North Carolina.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Wilmington, Delaware and Winston-Salem. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.