St. Louis to Syracuse, New York: Road Trip Guide & Distance

How far is St. Louis from Syracuse, New York?

The distance from St. Louis to Syracuse, New York is 794.2 miles (1278.2 km) as the crow flies. Syracuse, New York is located ENE of St. Louis. By car, the driving distance is approximately 953.1 miles, taking about 19h 10min. A direct flight would take roughly 2h 6min. Both are located in United States — St. Louis in Missouri and Syracuse, New York in New York.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility. For a trip of this distance, flying is significantly faster. However, driving offers the flexibility to explore stops along the way.

Coordinates come from public place data for St. Louis and Syracuse, New York. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.