Saint Joseph to Sioux Falls: Road Trip Guide & Distance

How far is Saint Joseph from Sioux Falls?

The distance from Saint Joseph to Sioux Falls is 278.3 miles (447.9 km) as the crow flies. Sioux Falls is located NNW of Saint Joseph. By car, the driving distance is approximately 347.9 miles, taking about 7h 0min. A direct flight would take roughly 1h 4min. Both are located in United States — Saint Joseph in Missouri and Sioux Falls in South Dakota.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Saint Joseph and Sioux Falls. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.