Ruston to Tupelo: Road Trip Guide & Distance

How far is Ruston from Tupelo?

The distance from Ruston to Tupelo is 256.6 miles (412.9 km) as the crow flies. Tupelo is located ENE of Ruston. By car, the driving distance is approximately 320.7 miles, taking about 6h 27min. A direct flight would take roughly 1h 1min. Both are located in United States — Ruston in Louisiana and Tupelo in Mississippi.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Ruston and Tupelo. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.